The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2005
Filed:
Nov. 15, 2001
John C. Reed, Rancho Santa Fe, CA (US);
Adam Godzik, San Diego, CA (US);
Krzysztof Pawlowski, Malmo, SE;
Loredana Fiorentino, San Diego, CA (US);
Sug Hyung Lee, Seoul, KR;
Wilfried Roth, La Jolla, CA (US);
Frank Stenner-liewen, Homburg/Saar, DE;
John C. Reed, Rancho Santa Fe, CA (US);
Adam Godzik, San Diego, CA (US);
Krzysztof Pawlowski, Malmo, SE;
Loredana Fiorentino, San Diego, CA (US);
Sug Hyung Lee, Seoul, KR;
Wilfried Roth, La Jolla, CA (US);
Frank Stenner-Liewen, Homburg/Saar, DE;
The Burnham Institute, La Jolla, CA (US);
Abstract
In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases.