The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2005
Filed:
Jul. 29, 2002
Byoung Joo Gwag, Seoul, KR;
Young AE Lee, Suwon-si, KR;
BO Rum Ryu, Suwon-si, KR;
Sung Hwa Yoon, Suwon-si, KR;
Ho Sang Moon, Suwon-si, KR;
Byoung Joo Gwag, Seoul, KR;
Young Ae Lee, Suwon-si, KR;
Bo Rum Ryu, Suwon-si, KR;
Sung Hwa Yoon, Suwon-si, KR;
Ho Sang Moon, Suwon-si, KR;
Neurotech Co., Ltd., , KR;
Abstract
The present invention provides compositions and methods for prevention and prophylaxis of neurological diseases accompanied by neuronal death. The invention includes synthesis of 5-benzylamino salicylic acid (BAS) and its derivatives. BAS and its derivatives protect cortical neurons from toxic insults by N-methyl-D-aspartate, Zn, and reactive oxygen species. Thus, the present invention provides compositions and methods for treating stroke, traumatic brain and spinal cord injury, epilepsy, and neurodegenerative diseases that are accompanied by severe neuronal loss via excitotoxicity, Znneurotoxicity, and free radical neurotoxicity.