The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 15, 2005

Filed:

Nov. 20, 2003
Applicants:

Takahide Nishi, Tokyo, JP;

Toshiyasu Takemoto, Tokyo, JP;

Takaichi Shimozato, Miura, JP;

Futoshi Nara, Yachiyo, JP;

Inventors:

Takahide Nishi, Tokyo, JP;

Toshiyasu Takemoto, Tokyo, JP;

Takaichi Shimozato, Miura, JP;

Futoshi Nara, Yachiyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/42 ; A61K031/135 ; C07D263/04 ; C07C215/00 ;
U.S. Cl.
CPC ...
Abstract

Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives:wherein Rand Rare a hydrogen atom, an amino protecting group; Ris a hydrogen atom, a hydroxy protecting group; Ris a lower alkyl group; n is an integer from 1 to 6; X is an ethylene group; Y is a C-Calkylene group, a C-Calkylene group substituted with 1 to 3 substituents selected from substituent group a and b; Ris an aryl group; Rand Rare a hydrogen atom, a group selected from substituent group a; with the proviso when Ris a hydrogen atom, Y is not a single bond or a straight chain C-Calkylene group.


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