The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2005
Filed:
Feb. 19, 2003
Michel Jolivet, Bron, FR;
Francois Penin, Decines, FR;
Pascal Dalbon, Lyons, FR;
Laurent Ladaviere, Villeurbanne, FR;
Xavier Lacoux, Lyons, FR;
Michel Jolivet, Bron, FR;
Francois Penin, Decines, FR;
Pascal Dalbon, Lyons, FR;
Laurent Ladaviere, Villeurbanne, FR;
Xavier Lacoux, Lyons, FR;
Bio Merieux, Marcy, FR;
Abstract
The invention concerns a structural peptide, identified by antibodies directed against a polypeptide, comprising the 2-45 amino acid sequence of the N-terminal end of the Core or nucleocapsid (p21) protein of the hepatitis C virus (HCV), excluding any protein or peptide compound comprising or consisting of the N-terminal end. The invention is characterized in that it comprises a tertiary structure consisting of at least a first peptide fragment having a secondary structure in α helix, a second peptide fragment having secondary structure in α helix and a third peptide bond fragment linking the two α helices, these two α helices being substantially perpendicular to each other in space. This peptide can be used for detecting antibodies directed against the p21 protein of HCV, for detecting all of part of the RNA of HCV and for preparing a diagnostic, prophylactic or therapeutic composition for detecting, preventing or treating an HCV infection.