The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2005
Filed:
Jul. 17, 2003
Applicants:
Anup Kumar Ray, Staten Island, NY (US);
Hiren Patel, Edison, NJ (US);
Mahendra R Patel, East Brunswick, NJ (US);
Inventors:
Anup Kumar Ray, Staten Island, NY (US);
Hiren Patel, Edison, NJ (US);
Mahendra R Patel, East Brunswick, NJ (US);
Assignee:
Sandoz AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/4545 ; A61K031/445 ; C07D401/04 ; C07D401/08 ; A61P037/08 ;
U.S. Cl.
CPC ...
Abstract
This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihyfro-11-(4-piperidylidene)-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine, hereinafter called 'desloratadine'. These polymorphic salt forms show much higher solubility in water and also in protic organic solvents compare to the parent desloratadine. The process of preparing the polymorphic forms comprising: