The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 08, 2005

Filed:

Jul. 24, 2001
Applicants:

Kiyoshi Furukawa, Shiga-gun, JP;

Satoshi Kurumiya, Nishinomiya, JP;

Takashi Hashimoto, Nishinomiya, JP;

Inventors:

Kiyoshi Furukawa, Shiga-gun, JP;

Satoshi Kurumiya, Nishinomiya, JP;

Takashi Hashimoto, Nishinomiya, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D473/00 ; A61K031/52 ; A61P025/28 ; A61P025/00 ;
U.S. Cl.
CPC ...
Abstract

Medicines for treatment or prevention of dementia comprising 2-aryl-8-oxodihydropurine derivatives of the formula (I):wherein W is H, Calkyl, halogen, Calkoxy, or the like; X is H, Calkyl, a group of the formula (Q): —CH(R)CON(R) (R) (wherein Ris a Calkyl or the like; Ris phenyl-substituted Calkyl or the like; and Ris H or the like); Y is H, Calkyl, a group of the above formula (Q), or the like; and A is substituted phenyl or the like, with the proviso that one of X and Y is a group of the formula (Q) and the other is a group selected from those defined for X or Y except the groups (Q), or pharmaceutically acceptable acid addition salts thereof. The above compounds exhibit an extremely potent ameliorating effect on learning disorder and/or dymnesia and thus are useful in the treatment or prevention of Alzheimer-type dementia, cerebrovascular dementia, senile dementia, etc.


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