The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 2005
Filed:
Jul. 01, 2002
Kisaburo Deguchi, Hitachinaka, JP;
Genzo Hirata, Hitachinaka, JP;
Junkichi Miura, Hitachinaka, JP;
Masahito Ito, Hitachinaka, JP;
Shinichiro Nishimura, Sapporo, JP;
Susumu Nishiguchi, Otsu, JP;
Atsushi Toda, Tsuruga, JP;
Hiroaki Nakagawa, Sapporo, JP;
Kuriko Yamada, Sapporo, JP;
Kisaburo Deguchi, Hitachinaka, JP;
Genzo Hirata, Hitachinaka, JP;
Junkichi Miura, Hitachinaka, JP;
Masahito Ito, Hitachinaka, JP;
Shinichiro Nishimura, Sapporo, JP;
Susumu Nishiguchi, Otsu, JP;
Atsushi Toda, Tsuruga, JP;
Hiroaki Nakagawa, Sapporo, JP;
Kuriko Yamada, Sapporo, JP;
Hitachi, Ltd., Tokyo, JP;
Toyobo Co., Ltd., Osaka, JP;
Abstract
A sugar chain synthesizer comprising one or more reaction columns packed with immobilized glycosyltransferase and/or glycosidase; one or more separation means, arranged downstream from the reaction columns, for separating reaction products, unreaction products and byproducts contained in the solution eluted from the reaction columns; a first pump for feeding a primer of water soluble polymer and buffer solution to the reaction columns through a first selector valve; a second pump for feeding a buffer solution and sugar nucleotide solution to any one of the reaction columns through a second selector valve; one or more circulation flow paths connecting between a flow path downstream from the separation means and a flow path upstream from each of the reaction columns; and a third selector valve, arranged between the separation means and one or more circulation flow paths, for selective connection between the separation means and a desired circulation flow path. This synthesizer ensures continuous and automatic synthesis of sugar chains even if complicated.