The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2005
Filed:
Oct. 23, 2002
Roger J Butlin, Macclesfield, GB;
Thorsten Nowak, Macclesfield, GB;
Jeremy N Burrows, Macclesfield, GB;
Michael H Block, Macclesfield, GB;
Roger J Butlin, Macclesfield, GB;
Thorsten Nowak, Macclesfield, GB;
Jeremy N Burrows, Macclesfield, GB;
Michael H Block, Macclesfield, GB;
AstraZeneca AB, Sodertalje, SE;
Abstract
The use of compounds of formula (I), and salts thereof; and pharmaceutically acceptable in vivo cleavable prodrugs of said compound of formula (I); and pharmaceutically acceptable salts of said compound or said prodrugs; in formula (I), Ring C is phenyl or a carbon linked heteroaryl ring substituted as defined within; Ris an ortho substituent as defined within; n is 1 or 2; A-B is a linking group as defined within; Rand Rare as defined within; Ris hydroxy, hydrogen, halo, amino or methyl; in the manufacture of a medicament for use in the elevation of PDH activity in warm-blooded animals such as humans is described. Pharmaceutical compositions, methods and processes for preparation of compounds of formula (I) are also described