The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 01, 2005

Filed:

Jul. 02, 2002
Applicants:

Susan J. Kirst, Brookline, MA (US);

Douglas A. Holtzman, Jamaica Plain, MA (US);

Christopher C. Fraser, Lexington, MA (US);

John D. Sharp, Arlington, MA (US);

Thomas S. Barnes, Boston, MA (US);

Inventors:

Susan J. Kirst, Brookline, MA (US);

Douglas A. Holtzman, Jamaica Plain, MA (US);

Christopher C. Fraser, Lexington, MA (US);

John D. Sharp, Arlington, MA (US);

Thomas S. Barnes, Boston, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K038/00 ; A61K039/00 ;
U.S. Cl.
CPC ...
Abstract

The invention provides isolated nucleic acids encoding a variety of proteins and nucleic acids having diagnostic, preventive, therapeutic, and other uses. These nucleic acids and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes.


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