The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2005
Filed:
Apr. 25, 2002
Applicants:
Vladimir Z. Volloch, Brookline, MA (US);
Michael Sherman, Newton, MA (US);
Inventors:
Vladimir Z. Volloch, Brookline, MA (US);
Michael Sherman, Newton, MA (US);
Assignee:
Phylogency, Inc., Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q001/00 ;
U.S. Cl.
CPC ...
Abstract
The present invention relates to drug screening assays and methods for the treatment of proliferative disorders associated with elevated levels of heat shock protein 72 (Hsp72) expression in a cell. The invention is based on the discovery that overexpression of full length Hsp72 protein, or the C-terminal protein binding domain of Hsp72, results in oncogenic transformation of cells.