The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 2005
Filed:
Dec. 10, 2001
Jainamma Krotz, San Diego, CA (US);
Daniel Smolko, Jamul, CA (US);
Howard R. Reese, Poway, CA (US);
Thomas J. Onofrey, San Marcos, CA (US);
Daguang Wang, San Diego, CA (US);
Theodore M. Winger, San Diego, CA (US);
John R. Havens, San Diego, CA (US);
Jainamma Krotz, San Diego, CA (US);
Daniel Smolko, Jamul, CA (US);
Howard R. Reese, Poway, CA (US);
Thomas J. Onofrey, San Marcos, CA (US);
Daguang Wang, San Diego, CA (US);
Theodore M. Winger, San Diego, CA (US);
John R. Havens, San Diego, CA (US);
Nanogen, Inc., San Diego, CA (US);
Abstract
The present invention provides improved synthetic polymer hydrogel permeation layers for use on active electronic matrix devices for biological assays. The permeation layers have a defined porous character, with mesopores in a size range between about 100 nanometers and about 1000 nanometers, and may also have micropores in the micrometer size range. The mesoporous synthetic hydrogel permeation layers demonstrate improved signal intensity and linearity characteristics as compared to nanoporous synthetic hydrogel permeation layers on active electronic matrix devices. In addition, the present invention also provides synthetic polymer hydrogel permeation layers which contain copolymerized attachment sites for nucleic acid probes or other biomolecules.