The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 2005

Filed:

Jul. 18, 2001
Applicants:

Galina N. Fomovskaia, Boston, MA (US);

Martin A. Smith, Brookline, MA (US);

Mikhail A. Fomovsky, Boston, MA (US);

Neil J. Butt, Cambridge, GB;

Inventors:

Galina N. Fomovskaia, Boston, MA (US);

Martin A. Smith, Brookline, MA (US);

Mikhail A. Fomovsky, Boston, MA (US);

Neil J. Butt, Cambridge, GB;

Assignee:

Whatman, Inc., Florham Park, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H021/02 ;
U.S. Cl.
CPC ...
Abstract

A method for isolating nucleic acid which comprises: Additionally, there is provided a substrate for lysing cells and purifying nucleic acid having a matrix and a coating and an integrity maintainer for maintaining the purified nucleic acid. Also provided is a method of purifying nucleic acid by applying a nucleic acid sample to a substrate having an anionic detergent affixed to a matrix, the substrate physically capturing the nucleic acid, bonding the nucleic acid to a substrate and generating a signal when the nucleic acid bonds to the substrate indicating the presence of the nucleic acid. A kit for purifying nucleic acid containing a coated matrix and an integrity maintenance provider for preserving the matrix and purifying nucleic acid is also provided. Further, there is provided a method for quantifying DNA, such as double-stranded or genomic DNA, isolated from cells, such as leukocytes to determine the numbers of leukocytes in a sample of leukoreduced blood.


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