The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2005
Filed:
Mar. 14, 2003
Samuel H. Gellman, Madison, WI (US);
Matthew G. Woll, Madison, WI (US);
Jonathan R. Lai, Madison, WI (US);
Justin Murray, Madison, WI (US);
Samuel H. Gellman, Madison, WI (US);
Matthew G. Woll, Madison, WI (US);
Jonathan R. Lai, Madison, WI (US);
Justin Murray, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
Disclosed are polypeptide compounds containing at least one residue comprising a cyclically-constrained γ-amino acid residue. The compounds have the formulawhere A is a hydrogen, hydroxy, amino- or carboxy-protecting group, Y is a single bond or a prolyl-containing linking group, and X and Y are γ-amino acid residues, provided that one of X or Y is a conformationally-restrained γ-amino acid residue, and 'a,' 'c,' and “d” are positive integers. The compounds find use as non-enzymatically degradable probes to mimic protein behavior in solution.