The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2005
Filed:
Feb. 02, 2001
Hirokazu Kubota, Ibaraki, JP;
Yasuhiro Yonetoku, Ibaraki, JP;
Keizo Sugasawa, Ibaraki, JP;
Masashi Funatsu, Ibaraki, JP;
Souichirou Kawazoe, Ibaraki, JP;
Akira Toyoshima, Ibaraki, JP;
Jun Ishikawa, Ibaraki, JP;
Makoto Takeuchi, Ibaraki, JP;
Hirokazu Kubota, Ibaraki, JP;
Yasuhiro Yonetoku, Ibaraki, JP;
Keizo Sugasawa, Ibaraki, JP;
Masashi Funatsu, Ibaraki, JP;
Souichirou Kawazoe, Ibaraki, JP;
Akira Toyoshima, Ibaraki, JP;
Jun Ishikawa, Ibaraki, JP;
Makoto Takeuchi, Ibaraki, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
The present invention is directed to drugs, in particular, pyrazole derivatives represented by the following general formula (I)which have a calcium release-activated calcium channel inhibitory effect and medicinal compositions, in particular, calcium release-activated calcium channel inhibitors containing the above compounds as the active ingredient, wherein each substituent is defined in the specification. The present invention also relates to a pharmaceutical composition containing an effective amount of the compound of formula (I) and a pharmaceutically effective carrier. The present invention further relates to methods of treatment of diseases associated with calcium release-activated calcium channels, diseases associated with IL-2 production, and methods of treatment of allergic, inflammatory or auto-immune diseases.