The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2005
Filed:
Jun. 18, 2003
Tian-qiang Sun, San Francisco, CA (US);
Lewis T. Williams, Mill Valley, CA (US);
Tian-Qiang Sun, San Francisco, CA (US);
Lewis T. Williams, Mill Valley, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention provides Dishevelled Associated Kinase polypeptides, which phosphorylate Dsh proteins involved in the Wnt/Wg signalling pathway. Isolated polynucleotides encoding DAK polypeptides are further provided, as are recombinant vectors, and host cells comprising the polynucleotides. Methods of using the polynucleotides and polypeptides of the invention are further aspects of the invention, including assays to detect agents which modulate DAK kinase activity. Further provided are methods of modulating pathways involved in control of cell proliferation.