The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 25, 2005
Filed:
Dec. 19, 2003
Karen Linder, Kingston, NJ (US);
Adrian D. Nunn, Ringoes, NJ (US);
David P. Nowotnik, Flemington, NJ (US);
Kondareddiar Ramalingam, Dayton, NJ (US);
Richard J. Dirocco, Allentown, NJ (US);
William L. Rumsey, Wyndmoor, PA (US);
John P. Pirro, Mahwah, NJ (US);
Karen Linder, Kingston, NJ (US);
Adrian D. Nunn, Ringoes, NJ (US);
David P. Nowotnik, Flemington, NJ (US);
Kondareddiar Ramalingam, Dayton, NJ (US);
Richard J. DiRocco, Allentown, NJ (US);
William L. Rumsey, Wyndmoor, PA (US);
John P. Pirro, Mahwah, NJ (US);
Bracco International B.V., Amsterdam, NL;
Abstract
Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.