The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2005
Filed:
Jan. 25, 2001
Kevin Delos Parris, Auburndale, MA (US);
William Stuart Somers, Cambridge, MA (US);
Amy Szepui Tam, Medford, MA (US);
Laura Long Lin, Weston, MA (US);
Mark Lloyd Stahl, Lexington, MA (US);
Kevin Delos Parris, Auburndale, MA (US);
William Stuart Somers, Cambridge, MA (US);
Amy Szepui Tam, Medford, MA (US);
Laura Long Lin, Weston, MA (US);
Mark Lloyd Stahl, Lexington, MA (US);
Wyeth, Madison, NJ (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
This invention is directed to Acyl Carrier Protein Synthase (ACPS) crystals and crystals of Acyl Carrier Protein Synthase-Coenzyme A (ACPS-CoA) complex, and to the use of these crystals to determine the three dimensional structure of ACPS. This invention is further directed to the use of rational drug design methods to identify agents that may interact with active sites of ACPS and ACPS-CoA complex, and to the testing of these agents to identify agents that may inhibit ACPS and/or ACPS-CoA complex activity.