The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2005
Filed:
Aug. 14, 2002
Ronald W. Pero, Arlington, VT (US);
David Sherris, Jamaica Plain, MA (US);
Kevin G. Pinney, Woodway, TX (US);
Vani P. Mocharla, Waco, TX (US);
Zhi Chen, West Haven, CT (US);
Ronald W. Pero, Arlington, VT (US);
David Sherris, Jamaica Plain, MA (US);
Kevin G. Pinney, Woodway, TX (US);
Vani P. Mocharla, Waco, TX (US);
Zhi Chen, West Haven, CT (US);
Baylor University, Waco, TX (US);
OXiGENE, Inc., Waltham, MA (US);
Abstract
Treatment of warm-blooded animals having a tumor or non-malignant hypervascularation, by administering a sufficient amount of a cytotoxic agent formulated into a phosphate prodrug form having substrate specificity for microvessel phosphatases, so that microvessels are destroyed preferentially over other normal tissues, because the less cytotoxic prodrug form is converted to the highly cytotoxic dephosphorylated form.