The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2005

Filed:

Jun. 11, 2002
Applicants:

Stacie S. Canan Koch, La Jolla, CA (US);

Therese N. Alexander, San Diego, CA (US);

Mark Barvian, Ann Arbor, MI (US);

Gary Bolton, Ann Arbor, MI (US);

Frederick Earl Boyer, Jr., Canton Township, MI (US);

Benjamin J. Burke, San Diego, CA (US);

Tod Holler, Ann Arbor, MI (US);

Tanya M. Jewell, Encinitas, CA (US);

Vara Prasad Josyula, Ann Arbor, MI (US);

David J. Kucera, Del Mar, CA (US);

Maria Angelica Linton, San Diego, CA (US);

Jeffrey J. Machak, Shelby Township, MI (US);

Lennert J. Mitchell, Jr., Chula Vista, CA (US);

Sean T. Murphy, Ypsilanti, MI (US);

Siegfried H. Reich, Solana Beach, CA (US);

Donald J. Skalitzky, San Diego, CA (US);

John H. Tatlock, San Diego, CA (US);

Michael D. Varney, Solana Beach, CA (US);

Scott C. Virgil, San Diego, CA (US);

Stephen E. Webber, San Diego, CA (US);

Stephen T. Worland, Del Mar, CA (US);

Michael Melnick, Ann Arbor, MI (US);

Inventors:

Stacie S. Canan Koch, La Jolla, CA (US);

Therese N. Alexander, San Diego, CA (US);

Mark Barvian, Ann Arbor, MI (US);

Gary Bolton, Ann Arbor, MI (US);

Frederick Earl Boyer, Jr., Canton Township, MI (US);

Benjamin J. Burke, San Diego, CA (US);

Tod Holler, Ann Arbor, MI (US);

Tanya M. Jewell, Encinitas, CA (US);

Vara Prasad Josyula, Ann Arbor, MI (US);

David J. Kucera, Del Mar, CA (US);

Maria Angelica Linton, San Diego, CA (US);

Jeffrey J. Machak, Shelby Township, MI (US);

Lennert J. Mitchell, Jr., Chula Vista, CA (US);

Sean T. Murphy, Ypsilanti, MI (US);

Siegfried H. Reich, Solana Beach, CA (US);

Donald J. Skalitzky, San Diego, CA (US);

John H. Tatlock, San Diego, CA (US);

Michael D. Varney, Solana Beach, CA (US);

Scott C. Virgil, San Diego, CA (US);

Stephen E. Webber, San Diego, CA (US);

Stephen T. Worland, Del Mar, CA (US);

Michael Melnick, Ann Arbor, MI (US);

Assignee:

Agouron Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D277/06 ;
U.S. Cl.
CPC ...
Abstract

Compounds of the formula:where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.


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