The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2005
Filed:
Jan. 18, 2000
Gyula Dekany, West Lake, AU;
John Papagerogiou, Indooroopilly, AU;
Laurent Francois Bornaghi, Forest Lake, AU;
Gyula Dekany, West Lake, AU;
John Papagerogiou, Indooroopilly, AU;
Laurent Francois Bornaghi, Forest Lake, AU;
Alchemia Pty. Ltd., Queensland, AU;
Abstract
The invention provides collections of orthogonally-protected monosaccharides as universal building blocks for the synthesis of glycoconjugates of non-carbohydrate molecules, neo-glycoconjugates and oligosaccharides. This orthogonal protection strategy allows for the specific deprotection of any substituent ono the saccharide ring, and greatly facilitates targeted or library-focused carbohydrate-related syntheses. In particular, the invention provides a universal monosaccharide building block of General Formula (I) or General Formula (II) in which A is a leaving group; X is hydrogen, O, N or N; Xis hydrogen, —CHO—, —CHNH—, —CH, —CHNor —COO—; and B, C, D and E are protecting groups that can be cleaved orthogonally, and in which B, C, D and E are absent when X is hydrogen or N, and E is absent when Xis hydrogen, CHor N.