The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2005

Filed:

Dec. 19, 1997
Applicants:

Alan M. Warshawsky, Cincinnati, OH (US);

Joseph T. Tsay, Cincinnati, OH (US);

Michael J. Janusz, Oregonia, OH (US);

Jian Shen, Cincinnati, OH (US);

Gary A. Flynn, Tucson, AZ (US);

Ramalinga M. Dharanipragada, Tucson, AZ (US);

Joseph P. Burkhart, Plainfield, IN (US);

Douglas W. Beight, Indianapolis, IN (US);

Meena V. Patel, Chicago, IL (US);

Inventors:

Alan M. Warshawsky, Cincinnati, OH (US);

Joseph T. Tsay, Cincinnati, OH (US);

Michael J. Janusz, Oregonia, OH (US);

Jian Shen, Cincinnati, OH (US);

Gary A. Flynn, Tucson, AZ (US);

Ramalinga M. Dharanipragada, Tucson, AZ (US);

Joseph P. Burkhart, Plainfield, IN (US);

Douglas W. Beight, Indianapolis, IN (US);

Meena V. Patel, Chicago, IL (US);

Assignee:

Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D243/00 ; C07D401/00 ; C07D223/12 ; A61K031/55 ; A61P019/02 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein.


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