The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6951953 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 04, 2005

Filed:

Jan. 07, 2004
Applicants:

Youn Soo Sohn, Seoul, KR;

Yong Joo Jun, Seoul, KR;

Joo Ik Kim, Gyeonggi-Do, KR;

Inventors:

Youn Soo Sohn, Seoul, KR;

Yong Joo Jun, Seoul, KR;

Joo Ik Kim, Gyeonggi-Do, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F015/00 ; C08L085/02 ; A61K031/28 ;
U.S. Cl.
CPC ...
Abstract

Disclosed are a new class of a polyphosphazene-platinum(II) conjugate antitumor agent having high tumor tissue selectivity due to its enhanced permeability and retention effect to tumor tissues, and a preparation method thereof:wherein x represents the number of the ethylene oxide repeating unit and is 7, 12 or 16; y is 0, 1 or 2; z represents molar content of polyethylene glycol in the range of 0.5-1.5; n represents degree of polymerization of polyphosphazene in the range of 30-100; and A-A represents a diamine.


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