The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2005

Filed:

Oct. 31, 2001
Applicants:

Johannes Aebi, Basel, CH;

Jean Ackermann, Riehen, CH;

Henrietta Dehmlow, Grenzach-Wyhlen, DE;

Hans-peter Maerki, Basel, CH;

Olivier Morand, Hegenheim, FR;

Inventors:

Johannes Aebi, Basel, CH;

Jean Ackermann, Riehen, CH;

Henrietta Dehmlow, Grenzach-Wyhlen, DE;

Hans-Peter Maerki, Basel, CH;

Olivier Morand, Hegenheim, FR;

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/428 ; C07D275/04 ;
U.S. Cl.
CPC ...
Abstract

The present invention relates to heteroaromate OSC inhibitors. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.


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