The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2005
Filed:
Nov. 06, 2003
Linghong Xie, Guilford, CT (US);
Bingsong Han, Hamden, CT (US);
Yuelian Xu, East Haven, CT (US);
George D. Maynard, Clinton, CT (US);
Linghong Xie, Guilford, CT (US);
Bingsong Han, Hamden, CT (US);
Yuelian Xu, East Haven, CT (US);
George D. Maynard, Clinton, CT (US);
Neurogen Corp., Branford, CT (US);
Abstract
The invention provides 4-imidazol-1-ylmethyl pyrimidine of the formulathat bind to GABAreceptors. In the above formula, R, RR, R, R, Rand Ar are defined herein. Such compounds may be used to modulate ligand binding to GABAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAreceptors (e.g., receptor localization studies).
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile