The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6951857 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 04, 2005

Filed:

May. 09, 2003
Applicants:

Eddy Jean Edgard Freyne, B-2360 Beerse, BE;

Gustaaf Maria Boeckx, B-2340 Beerse, BE;

Jean Pierre Frans Van Wauwe, B-2340 Beerse, BE;

Gaston Stanislas Marcella Diels, B-2340 Beerse, BE;

Inventors:

Eddy Jean Edgard Freyne, B-2360 Beerse, BE;

Gustaaf Maria Boeckx, B-2340 Beerse, BE;

Jean Pierre Frans Van Wauwe, B-2340 Beerse, BE;

Gaston Stanislas Marcella Diels, B-2340 Beerse, BE;

Assignee:

Other;

Attorneys:
Int. Cl.
CPC ...
C07D253/075 ; A61K031/53 ; A61P037/08 ;
U.S. Cl.
CPC ...
Abstract

The present invention is concerned with the use of compounds of formulathe N-oxides, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein p represents 0, 1, 2 or 3; q represents 0, 1, 2, 3 or 4; Rrepresents hydrogen, Calkyl, mono- or di(Calkyl)aminoCalkyloxy, mercapto, Calkylthio, Ccycloalkyl, aryl or Calkyl substituted with mono- or di(Calkyl)amino, Calkyloxy, aryl or Het; Rrepresents cyano or a radical of formula —C(═X)—Y—R; wherein X represents O or S; Y represents O, S, NRor a direct bond; Rrepresents hydrogen; Ccycloalkyl; aryl or optionally substituted Calkyl; and where Y is a direct bond, Rmay also be halo or Het; Rand Reach independently represents halo, haloCalkyl, Calkyl, hydroxy, Calkyloxy, Calkylcarbonyloxy, mercapto, Calkylthio, Calkylsulfonyl, Calkylsulfinyl, haloCalkylsulfonyl, aryl, cyano, nitro, amino, mono- and di(Calkyl)amino or (Calkylcarbonyl)amino; aryl represents phenyl or substituted phenyl; and Het represents an optionally substituted heterocycle; in the manufacture of a medicament useful for treating eosinophil-dependent inflammatory diseases. The invention also relates to novel compounds, their preparation and compositions comprising them.


Find Patent Forward Citations

Freyne, Eddy Jean Edgard. (2005). 6-azauracil derivatives as il-5 inhibitors (U.S. Patent No. 6951857). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6951857

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