The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2005
Filed:
Apr. 15, 2002
Thomas Geoffrey Colerick Bird, Reims, FR;
Thomas Geoffrey Colerick Bird, Reims, FR;
AstraZeneca AB, Sodertalje, SE;
Abstract
This invention relates to novel compounds of Formula (I) for use as vascular damaging agents:wherein: X is selected from: —O—, —S—, —S(O)—, —S(O)—, —N(R)— or —N(R)CHC(O)—; Ris independently selected from: amino, halo, hydroxy, —OPOH, Calkyl, Calkoxy, N-Calkylamino, N,N-di-Calkanoylamino or Calkylthio wherein the amino group is optionally substituted by an amino acid residue and the hydroxy group is optionally esterified; Ris selected from: hydrogen or Calkyl; Ris selected from: hydrogen or Calkyl; Ris selected from: hydrogen or Calkyl; n is 0, 1 or 2; and p is 0, 1, 2 or 3; or a salt, pro-drug or solvate thereof. The invention also relates to methods for preparing compounds of Formula (I), to their use as medicaments (including methods for the treatment of angiogenesis or disease states associated with angiogenesis) and to pharmaceutical compositions containing compounds of Formula (I).
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile