The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2005

Filed:

Sep. 29, 2004
Applicants:

Jing Wu, San Mateo, CA (US);

Jay S. Tung, Belmont, CA (US);

Eugene D. Thorsett, Moss Beach, CA (US);

Michael A. Pleiss, Sunnyvale, CA (US);

Jeffrey S. Nissen, Indianapolis, IN (US);

R. Jeffrey Neitz, San Francisco, CA (US);

Lee H. Latimer, Oakland, CA (US);

Varghese John, San Francisco, CA (US);

Stephen Freedman, Walnut Creek, CA (US);

Thomas C. Britton, Carmel, IN (US);

James A. Audia, Indianapolis, IN (US);

Jon K. Reel, Carmel, IN (US);

Thomas E. Mabry, Indianapolis, IN (US);

Bruce A. Dressman, Indianapolis, IN (US);

Cynthia L. Cwi, Indianapolis, IN (US);

James J. Droste, Indianapolis, IN (US);

Steven S. Henry, New Palestine, IN (US);

Stacey L. Mcdaniel, Indianapolis, IN (US);

William Leonard Scott, Indianapolis, IN (US);

Russell D. Stucky, Indianapolis, IN (US);

Warren J. Porter, Indianapolis, IN (US);

Inventors:

Jing Wu, San Mateo, CA (US);

Jay S. Tung, Belmont, CA (US);

Eugene D. Thorsett, Moss Beach, CA (US);

Michael A. Pleiss, Sunnyvale, CA (US);

Jeffrey S. Nissen, Indianapolis, IN (US);

R. Jeffrey Neitz, San Francisco, CA (US);

Lee H. Latimer, Oakland, CA (US);

Varghese John, San Francisco, CA (US);

Stephen Freedman, Walnut Creek, CA (US);

Thomas C. Britton, Carmel, IN (US);

James A. Audia, Indianapolis, IN (US);

Jon K. Reel, Carmel, IN (US);

Thomas E. Mabry, Indianapolis, IN (US);

Bruce A. Dressman, Indianapolis, IN (US);

Cynthia L. Cwi, Indianapolis, IN (US);

James J. Droste, Indianapolis, IN (US);

Steven S. Henry, New Palestine, IN (US);

Stacey L. McDaniel, Indianapolis, IN (US);

William Leonard Scott, Indianapolis, IN (US);

Russell D. Stucky, Indianapolis, IN (US);

Warren J. Porter, Indianapolis, IN (US);

Assignees:

Athena Neurosciences, Inc., South San Francisco, CA (US);

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P025/28 ; A61K031/55 ;
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.


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