The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2005

Filed:

Dec. 10, 2001
Applicants:

Derek J. Hei, Concord, CA (US);

Michael S. Clarke, San Francisco, CA (US);

Inventors:

Derek J. Hei, Concord, CA (US);

Michael S. Clarke, San Francisco, CA (US);

Assignee:

Cerus Corporation, Concord, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N001/02 ; A61K035/14 ; C12N007/06 ; C12M001/00 ; C07K001/00 ;
U.S. Cl.
CPC ...
Abstract

Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition, while substantially maintaining a desired biological activity of the biological composition. The device comprises highly porous adsorbent particles, and the adsorbent particles are immobilized by an inert matrix. The matrix containing the particles is contained in a housing, and the particles range in diameter from about 1 μm to about 200 μm. The matrix can be fibrous, and the particles can have a surface area greater than 750 m/g and a pore diameter between about 25 and 800 Å. The device can be used to adsorb and remove a pathogen-inactivating compound that is a nucleic acid-binding compound such as psoralen, an acridine derivative or a dye from a biological composition such as a blood product.


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