The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2005

Filed:

Apr. 11, 2002
Applicants:

Zhinong Gao, Monmouth Junction, NJ (US);

Chien-kuang Chen, Marlboro, NJ (US);

Inventors:

Zhinong Gao, Monmouth Junction, NJ (US);

Chien-Kuang Chen, Marlboro, NJ (US);

Assignee:

Bristol-Myers Squibb Co., Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D243/14 ;
U.S. Cl.
CPC ...
Abstract

A process for the production of tertiary amines by reductive amination of carbonyl compounds with secondary amines in the presence of a water scavenger, preferably trifluoroacetic acid anhydride, is disclosed. This process has applications in the preparation of imidazole-containing benzodiazepines, which are inhibitors of farnesyl protein transferase.


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