The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2005
Filed:
Aug. 25, 1998
Joseph Albert Monforte, Berkeley, CA (US);
Christopher Hank Becker, Palo Alto, CA (US);
Thomas Andrew Shaler, Menlo Park, CA (US);
Daniel Joseph Pollart, Alameda, CA (US);
Joseph Albert Monforte, Berkeley, CA (US);
Christopher Hank Becker, Palo Alto, CA (US);
Thomas Andrew Shaler, Menlo Park, CA (US);
Daniel Joseph Pollart, Alameda, CA (US);
Sequenom, Inc., San Diego, CA (US);
Abstract
The present invention provides modified oligonucleotide primers designed to incorporate a cleavable moiety so that a 3' portion of the primer (linked to an extension product) can be released from an upstream 5′ portion of the primer. Upon selective cleavage of the cleavable site, primer extension products that contain about five or fewer base pairs of the primer sequence are released, to provide more useful sizing and sequence information per fragment than extension products containing the entire primer.