The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2005
Filed:
Feb. 02, 2001
Kiyozo Asada, Shiga, JP;
Takashi Uemori, Otsu, JP;
Takashi Ueno, Kusatsu, JP;
Nobuto Koyama, Uji, JP;
Kimikazu Hashino, Takatsuki, JP;
Ikunoshin Kato, Uji, JP;
Kiyozo Asada, Shiga, JP;
Takashi Uemori, Otsu, JP;
Takashi Ueno, Kusatsu, JP;
Nobuto Koyama, Uji, JP;
Kimikazu Hashino, Takatsuki, JP;
Ikunoshin Kato, Uji, JP;
Takara Bio Inc., , JP;
Abstract
The present invention provides a method for increasing the efficiency of gene transfer into target cells with a retrovirus. The transduction is affected by infecting target cells with a retrovirus in the presence of a mixture of a functional material having a retrovirus binding domain, and a second functional material having target cell binding domain. The target cells may be selected from the group of unintentional hematopoietic progenitor cells and erythrocyte precursor, specifically pluripotent stem cells or embryopalstic stem cells.