The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2005

Filed:

Apr. 01, 2002
Applicants:

Yoshihito Eguchi, Kashiwa, JP;

Ken-ichi Chiba, Tsuchiura, JP;

Masaki Goto, Tsuchiura, JP;

Hiroshi Obaishi, Tsukuba, JP;

Yoshikazu Kuboi, Tsukuba, JP;

Inventors:

Yoshihito Eguchi, Kashiwa, JP;

Ken-ichi Chiba, Tsuchiura, JP;

Masaki Goto, Tsuchiura, JP;

Hiroshi Obaishi, Tsukuba, JP;

Yoshikazu Kuboi, Tsukuba, JP;

Assignee:

Eisai Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/24 ; A61K031/235 ; A61K031/12 ; C07C205/00 ; C07C069/76 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound which has cytokine production inhibitory activity and is useful for the treatment of diseases which is associated with cytokine. The compound is represented by the following general formula (I) [wherein A represents a cyclic group which may be substituted; the partial structure -DE- represents a group represented by —CHCH— or —CH═CH—; W represents a group represented by —CH—, —CHCH—, —CH═CH— or —CH═; the partial structure >XY— represents a group represented by >CH—(CH)—, >C═CH—, >CH—CH—CH(OH)—, >CH—CH—C(═O)—, >CH—O— or >CH—O—CO—, provided that when W is —CH═, then XY— represents C—(CH)—; Z represents a divalent aliphatic hydrocarbon group; Rand R, which may be the same or different, each represents a hydrogen atom, or a hydroxyl, alkoxy or alkoxyalkoxy group; m is an integer of 0 or 1].


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