The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2005

Filed:

Sep. 23, 2003
Applicants:

Daniel Yohannes, New London, CT (US);

George Maynard, Clinton, CT (US);

Jun Yuan, Guilford, CT (US);

Linghong Xie, Guilford, CT (US);

Kyungae Lee, Guilford, CT (US);

Manuka Ghosh, Branford, CT (US);

George Luke, Clinton, CT (US);

Xiaojun Liu, New London, CT (US);

Arthur Nagal, Gales Ferry, CT (US);

Lawrence Vincent, Moosup, CT (US);

Kevin Currie, North Branford, CT (US);

Zhe-quing Wang, East Haven, CT (US);

Inventors:

Daniel Yohannes, New London, CT (US);

George Maynard, Clinton, CT (US);

Jun Yuan, Guilford, CT (US);

Linghong Xie, Guilford, CT (US);

Kyungae Lee, Guilford, CT (US);

Manuka Ghosh, Branford, CT (US);

George Luke, Clinton, CT (US);

Xiaojun Liu, New London, CT (US);

Arthur Nagal, Gales Ferry, CT (US);

Lawrence Vincent, Moosup, CT (US);

Kevin Currie, North Branford, CT (US);

Zhe-Quing Wang, East Haven, CT (US);

Assignees:

Neurogen Corporation, Branford, CT (US);

Pfizer, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D471/04 ; A61K031/4353 ; A61P025/24 ;
U.S. Cl.
CPC ...
Abstract

Disclosed are heterocyclic compounds of the formulaand the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, T, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAbrain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAbrain receptor.


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