The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 6946445 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 20, 2005

Filed:

Mar. 12, 1999
Applicants:

Ian Clark-lewis, Vancouver, CA;

Jiang-hong Gong, Vancouver, CA;

Vincent Duronio, Delta, CA;

Inventors:

Ian Clark-Lewis, Vancouver, CA;

Jiang-Hong Gong, Vancouver, CA;

Vincent Duronio, Delta, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K007/00 ; C07K007/02 ; C07K007/04 ; A61K038/21 ; A01N061/00 ;
U.S. Cl.
CPC ...
Abstract

The invention provides a variety of therapeutic uses for CXCR4 antagonists. In various embodiments. CXCR4 antagonsits may be used as therapeutically as follows, or to manufacture a medicament for such therapeutic treatments: reducing interferon gamma production by T-cells, treatment of an autoimmune disease, treatment multiple sclerosis, treatment of cancer, inhibition of angiogenesis. The invention provides corresponding methods of medical treatment, in which a therapeutic dose of a CXCR4 antagonist is administered in a pharmacologically acceptable formulation. Accordingly, the invention also provides therapeutic compositions comprising a CXCR4 antagonist and a pharmacologically acceptable excipient or carrier. The CXCR4 antagonists for use in the invention may be peptide compounds comprising a substantially purified peptide fragment, modified fragment, analogue or pharmacologically acceptable salt of SDF-1.


Find Patent Forward Citations

Clark-Lewis, Ian. (2005). Therapeutic chemokine receptor antagonists (U.S. Patent No. 6946445). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6946445

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