The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2005
Filed:
Feb. 24, 1999
Venkatachala L. Narayanan, Gaithersburg, MD (US);
Edward A. Sausville, Silver Spring, MD (US);
Gurmeet Kaur, Germantown, MD (US);
Ravi K. Varma, Rockville, MD (US);
Venkatachala L. Narayanan, Gaithersburg, MD (US);
Edward A. Sausville, Silver Spring, MD (US);
Gurmeet Kaur, Germantown, MD (US);
Ravi K. Varma, Rockville, MD (US);
Abstract
Disubstituted lavendustin A analogs that are PTK inhibitors having antiproliferative activity are described. Preferred compounds of the disclosure, without limitation, satisfy either Formula 1 or Formula 2.The present disclosure also provides pharmaceutical compositions comprising effective amounts of disubstituted lavendustin A analogs and potentially comprising other active ingredients, other materials conventionally used in the formulation of pharmaceutical compositions, and mixtures thereof. The compounds and compositions of the disclosure can be used for treating subjects to, for example, inhibit the proliferation of living cells in the treatment of proliferative diseases.