The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2005

Filed:

Jan. 24, 2003
Applicants:

Che-ming Teng, Taipei, TW;

Shiow-lin Pan, Taipei, TW;

Jih-hwa Guh, Taipei, TW;

Sheng-chu Kuo, Taichung, TW;

Fang-yu Lee, Tachia Taichung, TW;

Inventors:

Che-Ming Teng, Taipei, TW;

Shiow-Lin Pan, Taipei, TW;

Jih-Hwa Guh, Taipei, TW;

Sheng-Chu Kuo, Taichung, TW;

Fang-Yu Lee, Tachia Taichung, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/416 ; C07D231/56 ;
U.S. Cl.
CPC ...
Abstract

The present invention features a method for treating sepsis. The method includes administrating to a subject in need thereof an effective amount of a fused pyrazolyl compound of formula (I):A is H, C˜Calkyl, orin which n is 0, 1, 2, or 3; each of Ar, Ar, and Ar, independently, is phenyl, pyridinyl, thienyl, furyl, or pyrrolyl; and each of R, R, R, R, R, and R, independently, is XYZ; or Rand Rtogether, Rand Rtogether, or Rand Rtogether are O(CH)O; in which X is a bond or C˜Calkylene, Y is a bond, O, S, OC(O), OC(O)(CH)C(O)O, C(O)O, C(O)S, C(O)NH, C(O)NC˜Calkyl, NH, or NC˜Calkyl, and Z is H, halogen, CN, NO, or C˜Calkyl; and provided that one of Rand Ris not H.


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