The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2005

Filed:

Jan. 23, 2003
Applicants:

Dhanapalan Nagarathnam, Bethany, CT (US);

Jacques Dumas, Bethany, CT (US);

Holia Hatoum-mokdad, Hamden, CT (US);

Stephen Boyer, Fairfield, CT (US);

Hans Pluempe, Wuppertal, DE;

Inventors:

Dhanapalan Nagarathnam, Bethany, CT (US);

Jacques Dumas, Bethany, CT (US);

Holia Hatoum-Mokdad, Hamden, CT (US);

Stephen Boyer, Fairfield, CT (US);

Hans Pluempe, Wuppertal, DE;

Assignee:

Bayer Pharmaceuticals Corporation, West Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K031/505 ; C07D239/48 ;
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.


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