The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2005
Filed:
Jun. 21, 2002
Applicants:
Nicholas Stephen Bodor, Gainesville, FL (US);
Maria Bartolomeo Grant, Archer, FL (US);
Inventors:
Nicholas Stephen Bodor, Gainesville, FL (US);
Maria Bartolomeo Grant, Archer, FL (US);
Assignee:
University of Florida, Gainesville, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K038/12 ; C07K005/12 ; C07K007/64 ;
U.S. Cl.
CPC ...
Abstract
The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridinepyridinium salt-type redox targetor moiety, a bulky lipophilic function and an amino acid/dipeptide/tripeptide spacer, are used in the prevention and treatment of diabetic retinopathy.