The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2005
Filed:
Jan. 09, 2001
Yuti Chernajovsky, London, GB;
Hanna Stina Dreja, Montpellier, FR;
Gillian Adams, London, GB;
Queen Mary and Westfield College, London, GB;
Abstract
This invention provides a nucleic acid construct comprising a first nucleic acid sequence encoding a pharmaceutically active agent and a second nucleotide sequence encoding a latency associated peptide, in which a nucleic acid sequence encoding a proteolytic cleavage site is provided between the first and second nucleic acid sequences. The invention further provides a fusion protein comprising a latency associated peptide and a proteolytic cleavage site wherein the fusion protein is associated with a pharmaceutically active agent. Also disclosed are processes for preparing the construct and fusion protein, methods of treatment using the construct and fusion protein and pharmaceutical compositions containing the construct and fusion protein.