The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2005
Filed:
Nov. 28, 2000
Shila Jalali, San Diego, CA (US);
Alan Harper, Jamul, CA (US);
Matt Simpson, San Diego, CA (US);
Paul Swanson, Santee, CA (US);
John Havens, San Diego, CA (US);
Shila Jalali, San Diego, CA (US);
Alan Harper, Jamul, CA (US);
Matt Simpson, San Diego, CA (US);
Paul Swanson, Santee, CA (US);
John Havens, San Diego, CA (US);
Nanogen, Inc., San Diego, CA (US);
Abstract
The field of the present invention relates generally to a microstructure apparatus which may be used in a high-throughput screening context to monitor the rate of reaction of an enzyme with its substrate in cases where the product of the reaction has an altered net charge. For example, the systems and methods disclosed herein may be used to detect the activity of phosphatase enzymes, proteases and kinases on charged peptide substrates. The microstructure devices of the present invention comprise a plurality of microstructures, wherein each microstructure comprises a capture matrix located between two electrodes.