The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2005

Filed:

Nov. 01, 2002
Applicants:

Todd P. Lary, Homestead, FL (US);

Christopher W. Snow, Homestead, FL (US);

John S. Riley, Miami, FL (US);

Robert C. Burr, Miami, FL (US);

Inventors:

Todd P. Lary, Homestead, FL (US);

Christopher W. Snow, Homestead, FL (US);

John S. Riley, Miami, FL (US);

Robert C. Burr, Miami, FL (US);

Assignee:

Coulter International Corp., Miami, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G06K009/00 ; G01N035/02 ; G01J003/30 ;
U.S. Cl.
CPC ...
Abstract

Methods, systems and apparatus are provided for sorting particles in a stream of a sample in a flow cytometer by producing from a stable sort having desirable sort characteristics multiple images of a portion of the stream; generating from the multiple images an averaged numerical reference standard representative of the stable sort; continuously collecting during the sorting multiple running images of the portion of the stream; generating from the multiple running images at least one numerical sample average representative of the sample sort of each collection of the multiple running images; and comparing each numerical sample average to the numerical reference standard and determining whether a sample average exhibits a deviation from the reference standard that requires an adjustment of the sort. The sort may then be adjusted to eliminate or reduce the deviation and maintain the stable sort of the reference histogram. A novel imaging apparatus may be employed in a flow cytometer performing this method.


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