The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2005
Filed:
Jun. 01, 2001
Harvey A. Fishman, Menlo Park, CA (US);
Mark Blumenkranz, Portola Valley, CA (US);
Stacey Francine Bent, Palo Alto, CA (US);
Christina Lee, San Francisco, CA (US);
Philip Huie, Jr., Cupertino, CA (US);
Daniel V. Palanker, Sunnyvale, CA (US);
Harvey A. Fishman, Menlo Park, CA (US);
Mark Blumenkranz, Portola Valley, CA (US);
Stacey Francine Bent, Palo Alto, CA (US);
Christina Lee, San Francisco, CA (US);
Philip Huie, Jr., Cupertino, CA (US);
Daniel V. Palanker, Sunnyvale, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Abstract
Methods and apparatus for modifying membranous tissue, growing cells on modified membranous tissue, and for transplantation of modified tissues and modified tissues with attached cells are provided. In particular, the invention provides methods and apparatus for modifying membranous tissue such as lens capsule tissue and inner limiting membrane tissue, for growing cells such as iris pigment epithelial (IPE) cells and retinal pigment epithelial (RPE) cells on modified membranous tissue, and for modifying membranous tissue and growing cells on biodegradable polymer substrates. A method of modifying membranous tissues comprises depositing micropatterns of biomolecules onto membranous tissue with a contacting surface such as a stamp; other methods include mechanical ablation, photoablation, ion beam ablation, and modification of membranous tissues via the action of proteolytic enzymes.