The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2005
Filed:
Jul. 18, 1997
Delin Zhu, Southampton, GB;
Robert E Hawkins, Cambridge, GB;
Stephen J. Russell, Cambridge, GB;
Freda K. Stevenson, Southampton, GB;
Gregory P Winter, Cambridge, GB;
Delin Zhu, Southampton, GB;
Robert E Hawkins, Cambridge, GB;
Stephen J. Russell, Cambridge, GB;
Freda K. Stevenson, Southampton, GB;
Gregory P Winter, Cambridge, GB;
Cancer Research Technology Limited, London, GB;
Abstract
The invention relates to a nucleic acid construct for delivery into living cells in vivo for inducing an immune response in a patient to an idiotypic determinant present on a malignant B cell in the patient; the construct directing the expression of a fusion protein, said fusion protein comprising the idiotypic determinant and at least one T helper cell epitope from tetanus toxin. The invention further relates to a method of making the nucleic acid construct, a method of treating a patient, and to a composition comprising the nucleic acid construct.