The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2005

Filed:

Apr. 03, 2000
Applicants:

James P. Pearson, Iowa City, IA (US);

Kendall M. Gray, Iowa City, IA (US);

Luciano Passador, Rochester, NY (US);

Kenneth D. Tucker, Germantown, MD (US);

Anatol Eberhard, Brooktondale, NY (US);

Barbara H. Iglewski, Fairport, NY (US);

Everett P. Greenberg, Iowa City, IA (US);

Inventors:

James P. Pearson, Iowa City, IA (US);

Kendall M. Gray, Iowa City, IA (US);

Luciano Passador, Rochester, NY (US);

Kenneth D. Tucker, Germantown, MD (US);

Anatol Eberhard, Brooktondale, NY (US);

Barbara H. Iglewski, Fairport, NY (US);

Everett P. Greenberg, Iowa City, IA (US);

Assignees:

University of Iowa Research Foundation, Iowa City, IA (US);

University of Rochester, Rochester, NY (US);

Ithaca College, Ithaca, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N009/00 ; C12N001/00 ; C12N001/20 ;
U.S. Cl.
CPC ...
Abstract

Autoinducer molecules, e.g., N-(3-oxododecanoyl)homoserine lactone, forare described. The molecules regulate gene expression in the bacterium. Therapeutic compositions and therapeutic methods involving analogs and/or inhibitors of the autoinducer molecules also are described. The molecules are useful for treating or preventing infection by


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