The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2005

Filed:

May. 02, 2002
Applicants:

David A. Watson, Westwood, MA (US);

Thomas J. Smith, Weston, MA (US);

Richard Laporte, Waltham, MA (US);

Jianbing Chen, Belmont, MA (US);

Paul Ashton, Boston, MA (US);

Inventors:

David A. Watson, Westwood, MA (US);

Thomas J. Smith, Weston, MA (US);

Richard Laporte, Waltham, MA (US);

Jianbing Chen, Belmont, MA (US);

Paul Ashton, Boston, MA (US);

Assignee:

Control Delivery Systems, Inc., Watertown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K002/02 ;
U.S. Cl.
CPC ...
Abstract

A therapeutically effective compound is locally administered by associating the compound with a piece of orthopedic hardware that is implanted at an appropriate site within a body. The compound is adapted, such as through a sustained release device, to administer an effective dosage continuously over an extended period of time. The compound may be administered, for example, to a joint of a mammal by intraarticularly implanting a sustained release device to deliver the therapeutically effective compound within a synovial capsule of the joint, such that synovial fluid concentration of the compound is greater than plasma concentration of the compound. A wide range of orthopedic hardware, such as bone screws and staples, may be adapted to use in the systems described herein to provide treatment for a variety of medical conditions.


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