The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2005
Filed:
Oct. 31, 2002
Kyung Bae Park, Daejeon, KR;
Sang Hyun Park, Seongnam-si, KR;
Hui Jeong Gwon, Daejeon, KR;
Sun Ju Choi, Daejeon, KR;
Byung Chul Shin, Daejeon, KR;
Young Don Hong, Daejeon, KR;
Sang Mu Choi, Daejeon, KR;
Woong Woo Park, Seoul, KR;
Kwang Hee Han, Daejeon, KR;
Beom Su Jang, Daejeon, KR;
Kyung Bae Park, Daejeon, KR;
Sang Hyun Park, Seongnam-si, KR;
Hui Jeong Gwon, Daejeon, KR;
Sun Ju Choi, Daejeon, KR;
Byung Chul Shin, Daejeon, KR;
Young Don Hong, Daejeon, KR;
Sang Mu Choi, Daejeon, KR;
Woong Woo Park, Seoul, KR;
Kwang Hee Han, Daejeon, KR;
Beom Su Jang, Daejeon, KR;
Korea Atomic Energy Research Institute, Daejeon, KR;
Abstract
The present invention relates to a method of preparing technetium or rhenium complex for radiopharmaceuticals, through reaction of pertechnetate or perrhenate with a ligand in the presence of a reducing agent, wherein the reducing agent is a borohydride exchange resin (BER). The borohydride exchange resin of the present invention has advantages of being stable in a wide range of Ph, including acidic or alkaline condition(Ph 2˜14) and thus being applicable to biological materials as well as being easily removable through filtration when being administrated. Also since the radiolabelled complex is produced under conditions milder than those required for the conventional reducing agents as well as has high radiochemical purity and high labeling efficiency, the conventional reducing agents can be replaced by the BER of the present invention.