The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2005
Filed:
Jul. 18, 2003
Rajeev S. Bhide, Princeton Junction, NJ (US);
Junying Fan, Monmouth Junction, NJ (US);
Luca Parlanti, Princeton, NJ (US);
Stephanie Barbosa, Lambertville, NJ (US);
Ligang Qian, Hopewell, NJ (US);
Zhen-wei Cai, Belle Mead, NJ (US);
Francis S. Gibson, Pennington, NJ (US);
Rajeev S. Bhide, Princeton Junction, NJ (US);
Junying Fan, Monmouth Junction, NJ (US);
Luca Parlanti, Princeton, NJ (US);
Stephanie Barbosa, Lambertville, NJ (US);
Ligang Qian, Hopewell, NJ (US);
Zhen-Wei Cai, Belle Mead, NJ (US);
Francis S. Gibson, Pennington, NJ (US);
Bristol Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention relates to a process for preparing certain pyrrolotriazine compounds of the formulaand pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.