The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2005
Filed:
Oct. 03, 2001
Applicants:
Emmanuel Conseiller, Paris, FR;
Laurent Bracco, Paris, FR;
Inventors:
Emmanuel Conseiller, Paris, FR;
Laurent Bracco, Paris, FR;
Assignee:
Aventis Pharma S.A., Antony, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07H021/04 ; C12N015/74 ;
U.S. Cl.
CPC ...
Abstract
Proteins derived from the product of tumor suppressor gene p53 and having enhanced functions for therapeutical use are disclosed. The proteins advantageously have enhanced tumour suppressor and programmed cell death inducer functions, particularly in proliferative disease contexts where wild-type p53 protein is inactivated. Nucleic acids coding for such molecules, vectors containing same, and therapeutical use thereof, particularly in gene therapy, are also disclosed.