The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2005

Filed:

Mar. 27, 2001
Applicants:

Jonathan L. Coffman, Haverhill, MA (US);

William Barry Foster, Chelmsford, MA (US);

Bonnie J. Germain, Webster, NH (US);

Shujun Sun, Brentwood, NH (US);

Jeffrey J. Robinson, Amesbury, MA (US);

Inventors:

Jonathan L. Coffman, Haverhill, MA (US);

William Barry Foster, Chelmsford, MA (US);

Bonnie J. Germain, Webster, NH (US);

Shujun Sun, Brentwood, NH (US);

Jeffrey J. Robinson, Amesbury, MA (US);

Assignee:

Genetics Institute, LLC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A23J001/00 ; C07K001/00 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides a process for isolating and purifying highly anionic target proteins, for example, sulfated proteins. Sulfated proteins have five (5) or more, sulfations. In a preferred embodiment, the sulfated protein has six (6) sulfations, e.g., six sulfations on N-terminal tyrosine residues, as embodied in PSGL-1 (P-selectin glycoprotein ligand).


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