The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2005
Filed:
Oct. 02, 2001
Morten Bech, Holte, DK;
Jørgen Due, Ølstykke, DK;
Lars Thomsen, Aalborg Ø, DK;
Jonatan Kutchinsky, Frederiksberg C, DK;
Rafael Taboryski, Lyngby, DK;
Bent Erling Nielsen, Lyngby, DK;
John Shaw, West Drayton, GB;
John Dodgson, Croydon, GB;
Morten Bech, Holte, DK;
Jørgen Due, Ølstykke, DK;
Lars Thomsen, Aalborg Ø, DK;
Jonatan Kutchinsky, Frederiksberg C, DK;
Rafael Taboryski, Lyngby, DK;
Bent Erling Nielsen, Lyngby, DK;
John Shaw, West Drayton, GB;
John Dodgson, Croydon, GB;
Sophion Bioscience A/S, Ballerup, DK;
Abstract
The present invention relates to a high through-put system for determining and/or monitoring electrophysiological properties of ion channels of ion channel-containing membranes, typically lipid membrane-containing structures such as cells. In particular, the invention provides a substrate which provides means for automatically positioning cells at measuring sites using electroosmotic flow in canals formed on or in the substrate. The electroosmotic flow is generated and controlled by electroosmotic flow pumps integrated on the substrate or positioned in relation thereto. Thereby, cells can be positioned in favorable measurement configuration at a plurality of sites for performing testing and measurements. Also, the invention relates to a main electric circuit for performing testing and measurements on a plurality of cells in parallel.